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Melatonin has been shown to have anti-inflammatory results, amongst a number of activities. Melatonin reduces tissue destruction throughout inflammatory responses by a variety of means. Hence melatonin, through its ability to directly feed on hazardous free radicals, minimizes macromolecular damage in all organs. The totally free radicals and also responsive oxygen and nitrogen species recognized to be scavenged by melatonin consist of the extremely toxic hydroxyl radical, peroxynitrite anion, and hypochlorous acid, among others. These representatives all add to the inflammatory feedback as well as linked cells destruction. In addition, melatonin has other ways to decrease the damages arising from swelling.
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