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Melatonin has been revealed to possess anti-inflammatory impacts, amongst a number of activities. Melatonin decreases tissue destruction during inflammatory reactions by a number of means. Thus melatonin, because of its capacity to directly feed on toxic totally free radicals, decreases macromolecular damages in all organs. The free radicals as well as reactive oxygen and nitrogen varieties recognized to be fed on by melatonin include the very harmful hydroxyl radical, peroxynitrite anion, as well as hypochlorous acid, among others. These agents all contribute to the inflammatory reaction and also associated tissue destruction. In addition, melatonin has various other means to reduce the damage resulting from inflammation.
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